Tiherb Biotech

Serving the global pharmaceutical, health food, cosmetics, and beverage industries

2025-08-10

Unlocking the Secrets of Nobiletin: The Citrus Compound Making Waves

Discover the fascinating benefits of Nobiletin, a citrus compound that may revolutionize health and wellness. Learn more!


2025-08-03

Unlocking the Secrets of Nobiletin: Nature’s Hidden Gem

Discover the benefits and uses of Nobiletin, a powerful compound found in citrus fruits.


2025-07-27

Unlocking the Secrets of Nobiletin: A Citrus Gem

Discover the health benefits and wonders of Nobiletin, a powerful compound found in citrus fruits.


2025-04-28

The antimicrobial, antioxidant, and immunostimulatory mechanisms of plant extracts

Plant extracts enhance the immune system of animals. Plant polysaccharides improve the phagocytic ability of macrophages in animals, enhance the production of reactive oxygen species and nitric oxide, stimulate cytokines, increase the number of lymphocytes, activate antibody production, and prolong the effect of antibodies.


2025-04-28

Classification and Extraction Methods of Plant Extracts

Plant extracts are products obtained by physically and chemically extracting and separating one or more active components from plants, based on the intended use of the final product, without altering the structure of the active components.


2025-04-28

How are plant extracts extracted?

Plant extracts are obtained from plants through physical and chemical extraction and separation processes, according to the intended use and requirements of the final extracted product. The process aims to obtain or concentrate one or more active ingredients in the plant, which can be used in the food, pharmaceutical, and daily chemical industries. With the continued growth in global demand for natural health products, the plant extract industry shows tremendous development potential. In 2023, the global plant extract market size exceeded \$50 billion USD, with a year-on-year growth rate exceeding 15%, demonstrating strong development momentum. Currently, commonly used methods for extracting plant extracts include solvent extraction, microwave extraction, ultrasonic extraction, and enzymatic extraction. Among them, microwave-assisted extraction and supercritical fluid extraction, as new extraction technologies, have been widely used. 01. Solvent Extraction Method Solvent extraction uses a solvent to extract active ingredients from solid raw materials. The solvent used must be miscible with the solute to be extracted. After the plant material is pulverized, it is placed in a suitable container, and several times the amount of solvent is added. Extraction can be carried out using maceration, percolation, decoction, reflux, and continuous extraction methods. In the solvent extraction process, the concentration of the solvent, the solid-liquid ratio, the extraction temperature, and the extraction time directly affect the extraction rate of the active ingredients. 02. Ultrasonic Extraction Method Ultrasonic extraction utilizes the strong vibrations and cavitation effects generated by ultrasound to accelerate the release, diffusion, and dissolution of substances within plant cells into the solvent. Simultaneously, it maintains the structure and biological activity of the extracted substances. The principle of ultrasonic extraction is mainly a physical process and is a relatively new extraction method that has gradually gained attention in recent years. For most components, the ultrasonic extraction method significantly shortens the extraction time and consumes less solvent compared to conventional solvent extraction methods, resulting in high leaching rates and high extraction efficiency. In the ultrasonic extraction process, the choice and concentration of the solvent, the solid-liquid ratio, the extraction temperature, and the extraction time directly affect the extraction rate. Experimental results show that the extraction rate increases with increasing temperature and power. The ultrasonic extraction method is 6 times faster than the enzymatic extraction method, and the extraction rate is 2-3 times that of the enzymatic extraction method. Compared with the commonly used organic solvent extraction method, the ultrasonic extraction method not only has high extraction rate, speed, and efficiency, but also is a room temperature extraction, requiring no heating, thus saving energy. 03. Supercritical Fluid Extraction Method Supercritical fluid extraction (SFE) is a relatively new extraction and separation technology, generally using CO2 as the extractant. The principle of supercritical fluid extraction is to utilize the unique solubility of supercritical fluids and the sensitivity of the solubility of substances in supercritical fluids to changes in pressure and temperature. By means of temperature reduction and pressure reduction (or both), the dissolved substances in the supercritical fluid are separated to achieve the purpose of separation and purification. It combines both distillation and extraction, with advantages such as less inactivation of active ingredients, high product quality, and simultaneous completion of the extraction and separation process. It is considered a green and environmentally friendly high-tech separation technology, particularly suitable for the separation and purification of unstable natural products and physiologically active substances. 04. Microwave-Assisted Extraction Method Microwave-assisted extraction (MAE) is a new technology that uses microwave energy to improve extraction efficiency. Microwave-assisted extraction uses the characteristics of microwave heating to selectively extract target components from materials. By adjusting the microwave parameters, the target components can be effectively heated to facilitate their extraction and separation. The principle of microwave-assisted extraction of plants is that the plant sample absorbs a large amount of energy in the microwave field, while the surrounding solvent absorbs less, thus generating thermal stress inside the cells. The plant cells rupture due to the internal thermal stress, allowing the substances inside the cells to directly contact the relatively cold extraction solvent, thereby accelerating the transfer of the target product from the inside of the cells to the extraction solvent, thus enhancing the extraction process. Microwave-assisted extraction uses thermal energy, similar to soaking and filtration, but the speed of extracting plant extracts is much faster than traditional methods, reducing extraction time while preventing the destruction and degradation of valuable plant extracts. Currently, microwave-assisted extraction, with its fast extraction speed and good extract quality, has become a powerful tool for extracting natural plant active ingredients. However, microwave-assisted extraction is selective internal heating and requires the material being processed to have good water absorption. In other words, the location of the product to be separated must easily absorb water; otherwise, the cells will not be able to absorb enough microwaves to break themselves, and the product will not be able to be released quickly. For liquid extraction systems, the solvent must be polar; non-polar solvents are not sensitive to microwaves. 05. Microwave-Ultrasonic Synergistic Extraction Method Microwaves are non-ionizing electromagnetic radiation. The polar molecules of the irradiated substance rapidly rotate and align in the microwave electromagnetic field, causing tearing and friction, resulting in heating. This ensures rapid energy transfer and utilization, with advantages such as energy saving and no industrial pollution. However, the penetration depth of microwaves is limited (on the same order of magnitude as its wavelength), and its mass transfer function is not obvious in the enhanced extraction process. Ultrasound is a high-frequency mechanical wave with turbulent effects, micro-perturbation effects, interface effects, and energy focusing effects. However, the thermal effect produced by ultrasound is not obvious and is limited to a very small range around the cavitation bubbles. Combining the two, the synergistic effect is beneficial for the release of cell wall components, i.e., microwave-ultrasound synergistic enhanced extraction technology can obtain a low-cost and pollution-free method for extracting bioactive substances. 06. Enzymatic Extraction Method Plant cell walls are composed of cellulose, and plant active ingredients are often enclosed within the cell walls. Enzymatic extraction uses cellulase, pectinase, protease, etc. (mainly cellulase) to break down the plant cell walls, promoting the maximum dissolution and separation of plant active ingredients. In the enzymatic extraction process, the choice of enzyme, enzyme concentration, pH value, enzymatic hydrolysis temperature, and enzymatic hydrolysis time all affect the extraction rate of plant extracts. Enzymatic extraction is often used in the preparation of plant extracts, especially in cases where cell walls need to be broken down to release active ingredients. The plant extract industry is showing a trend towards personalization and customization, and product innovation of compound extracts will become an important trend. By 2025, China will become the world's largest producer and exporter of plant extracts, and the industry concentration and international competitiveness will further improve.


2025-04-28

How to ensure the quality and safety of plant extracts?

From the fields to the production workshop, from laboratory testing to market circulation, the quality and safety of extracts require the joint protection of the entire industrial chain. With the upgrading of consumers' demand for natural and safe products, enterprises need to be driven by technological innovation and take regulations and standards as the bottom line to build a quality management system that is "controllable at the source, standardized in the process, precise in detection, and traceable in responsibility", so that every drop of extract becomes trustworthy natural essence, and promotes the industry to move towards green, high-end, and internationalization.


2025-04-28

What are the top ten popular plant extracts?

Plant extracts are products obtained by physically and chemically extracting and separating one or more active components from plants, based on the intended use of the final product. This process aims to concentrate the desired components without altering their structure.


2025-04-28

What are the specific effects and functions of animal extracts on the human body?

Animal extracts, with their unique bioactivities, hold significant value in maintaining human health. However, scientific and rational use is crucial, balancing efficacy with risks to guide the industry towards safe, efficient, and sustainable development.


2025-04-28

Development prospects of the extract

Extracts, as the essence distilled from various substances, are experiencing a period of rapid growth and show extremely broad prospects in multiple dimensions.


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